diff --git a/pytest.ini b/pytest.ini
index adff9ae7f..9dc54548f 100644
--- a/pytest.ini
+++ b/pytest.ini
@@ -41,7 +41,7 @@ markers =
     qt6_only: Tests which should only run with Qt 6
     qt5_xfail: Tests which fail with Qt 5
     qt6_xfail: Tests which fail with Qt 6
-    qt68_beta4_skip: Fails on Qt 6.8 beta 4
+    qt68_no_permission_api: Fails on Qt 6.8 with PyQt<6.8
 qt_log_level_fail = WARNING
 qt_log_ignore =
     # GitHub Actions
diff --git a/qutebrowser/browser/webengine/webenginesettings.py b/qutebrowser/browser/webengine/webenginesettings.py
index b4f6f8a1b..63f740a2e 100644
--- a/qutebrowser/browser/webengine/webenginesettings.py
+++ b/qutebrowser/browser/webengine/webenginesettings.py
@@ -26,7 +26,7 @@ from qutebrowser.config import config, websettings
 from qutebrowser.config.websettings import AttributeInfo as Attr
 from qutebrowser.misc import pakjoy
 from qutebrowser.utils import (standarddir, qtutils, message, log,
-                               urlmatch, usertypes, objreg, version)
+                               urlmatch, usertypes, objreg, version, utils)
 if TYPE_CHECKING:
     from qutebrowser.browser.webengine import interceptor
 
@@ -281,6 +281,7 @@ class ProfileSetter:
         self._set_hardcoded_settings()
         self.set_persistent_cookie_policy()
         self.set_dictionary_language()
+        self.disable_persistent_permissions_policy()
 
     def _set_hardcoded_settings(self):
         """Set up settings with a fixed value."""
@@ -345,6 +346,14 @@ class ProfileSetter:
         self._profile.setSpellCheckLanguages(filenames)
         self._profile.setSpellCheckEnabled(bool(filenames))
 
+    def disable_persistent_permissions_policy(self):
+        """Disable webengine's permission persistence."""
+        pyqt_version = utils.VersionNumber.parse(version.PYQT_WEBENGINE_VERSION_STR)
+        if pyqt_version >= utils.VersionNumber(6, 8):
+            self._profile.setPersistentPermissionsPolicy(
+                QWebEngineProfile.PersistentPermissionsPolicy.AskEveryTime
+            )
+
 
 def _update_settings(option):
     """Update global settings when qwebsettings changed."""
diff --git a/tests/end2end/conftest.py b/tests/end2end/conftest.py
index 17703d1e1..83c66380d 100644
--- a/tests/end2end/conftest.py
+++ b/tests/end2end/conftest.py
@@ -192,8 +192,8 @@ def pytest_collection_modifyitems(config, items):
          'Skipped on Windows',
          pytest.mark.skipif,
          utils.is_windows),
-        ('qt68_beta4_skip',  # WORKAROUND: https://github.com/qutebrowser/qutebrowser/issues/8242#issuecomment-2184542226
-         "Fails on Qt 6.8 beta 4",
+        ('qt68_no_permission_api',  # WORKAROUND: https://github.com/qutebrowser/qutebrowser/issues/8242#issuecomment-2184542226
+         "Fails on Qt 6.8 with PyQt<6.8",
          pytest.mark.xfail,
          machinery.IS_QT6 and version.qtwebengine_versions(
              avoid_init=True
diff --git a/tests/end2end/features/prompts.feature b/tests/end2end/features/prompts.feature
index 9e2062d13..2b65bcc56 100644
--- a/tests/end2end/features/prompts.feature
+++ b/tests/end2end/features/prompts.feature
@@ -251,7 +251,7 @@ Feature: Prompts
         And I run :click-element id button
         Then the javascript message "geolocation permission denied" should be logged
 
-    @qt68_beta4_skip
+    @qt68_no_permission_api
     Scenario: geolocation with ask -> false
         When I set content.geolocation to ask
         And I open data/prompt/geolocation.html in a new tab
@@ -260,7 +260,7 @@ Feature: Prompts
         And I run :prompt-accept no
         Then the javascript message "geolocation permission denied" should be logged
 
-    @qt68_beta4_skip
+    @qt68_no_permission_api
     Scenario: geolocation with ask -> false and save
         When I set content.geolocation to ask
         And I open data/prompt/geolocation.html in a new tab
@@ -270,7 +270,7 @@ Feature: Prompts
         Then the javascript message "geolocation permission denied" should be logged
         And the per-domain option content.geolocation should be set to false for http://localhost:(port)
 
-    @qt68_beta4_skip
+    @qt68_no_permission_api
     Scenario: geolocation with ask -> abort
         When I set content.geolocation to ask
         And I open data/prompt/geolocation.html in a new tab