SeedRandom[1234];
a=Characters@"abcdefghijklmnopqrstuvwxyzABCDEFGHIJKLMNOPQRSTUVWXYZ0123456789 ";
map=Thread[a->RandomSample[a]];
ClearAll[SubstitutionCipherEncode,SubstitutionCipherDecode]
SubstitutionCipherEncode[input_String,map_]:=StringReplace[input,map]
SubstitutionCipherDecode[input_String,map_]:=StringReplace[input,Reverse/@map]

str="The quick brown fox jumps over the lazy dog,who barks VERY loudly!";
encoded=SubstitutionCipherEncode[str,map]
decoded=SubstitutionCipherDecode[encoded,map]
str===decoded