>> x = [0,  1,  2,  3,  4,  5,  6,   7,   8,   9,   10];
>> y = [1,  6,  17, 34, 57, 86, 121, 162, 209, 262, 321];
>> polyfit(x,y,2)

ans =

   2.999999999999998   2.000000000000019   0.999999999999956